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In vitro studies on human first trimester forebrain cells : differentiation and interactions with immunoregulating molecules
(1998-11-30)
where incubation with IFN-[gamma] showed expression of MHC class II molecules. Furthermore, natural induction of IL-1ß, IL-4, IL-6, IL-10, TNF-[alpha], IFN-[gamma] and TGF-ß in human first trimester forebrain cells was evaluated. Constitutive cytokine...
Objectively measured eating behaviors and their relation to food intake in school and hospital settings
(2021-05-28)
: -428.3 kcal to -17.2 kcal). Hospital: Advanced PD patients consumed significantly less energy during lunch compared to both early PD patients (b = -202.7 kcal, 95% confidence interval: -329.2 kcal to -76.2 kcal) and healthy controls (b = -162.1 kcal, 95...
Blocking interleukin-1 signalling in the brain-structural and functional outcomes
(2008-10-07)
The aims of this thesis were to evaluate the consequences of blocking interleukin (IL)-1 signalling in the brain. The studies used a transgenic mouse model with brain-directed overexpression of the human soluble isoform of IL-1 receptor antagonist...
Venous thrombosis in children : the roles of vascular access and critical illness
(2022-11-18)
Venous thromboembolism (VT) is a rare event in the general pediatric population. However, the incidence in hospitalized children is higher and has increased dramatically reaching 58 per 10 000 children. The single most ...
Sex differences in cancer risk and survival
(2019-11-15)
: In study I we found that men are at a higher risk of 34 of 39 malignancies, and have a poorer survival in 27 of 39. Except for smoking-associated malignancies, the excess risk in men is stable over calendar time. In male predominant sites, IRRs range from 1...
New potential targets in medulloblastoma therapy : studies on cellular mechanisms and mediators
(2010-01-15)
Medulloblastoma is an embryonal tumour that mainly affects children. It
is the most common malignant brain tumour in children and accounts for
15% of all childhood brain tumours. It most often presents in the
cerebellum ...
The development of psychiatric disorders and adverse behaviors : from context to prediction
(2022-01-28)
examined the individual and familial association between type 1 diabetes (T1D) and eating disorder diagnoses. We used national health care records from Denmark (n = 1,825,920) and Sweden (n = 2,517,277) to calculate the association within individuals, full...
Healthcare financing challenges and opportunities to achieving universal health coverage in the low- and middle-income country context
(2020-02-05)
estimated the impoverishment effect of OOP payments using both the national (cost of basic need approach) and the international (1.90 International dollar per person per day) poverty line. For study II, 557 informal workers were surveyed during 2010...
Clinical studies on drug treatment of hospitalised patients : general infectious diseases and acute myocardial infarction
(2013-05-03)
Treatment of hospitalised patients is generally governed by the pre-developed algorithms and common guidelines. These approaches are helpful in most, but not all cases. Treatment of hospitalised patients is limited to the ...
Early-life selenium status and cognitive development
(2018-11-12)
world-wide, particularly in Europe and south-eastern Asia. It has been estimated that 0.5-1 billion people could be selenium deficient. Previous studies regarding health effects of selenium have focused on the impact of deficiency for the risk of cancer...