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The internationalization of work : psychophysiological predictors of adjustment to foreign assignment
(1998-11-27)
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The aims of the thesis were 1) to study psychological, social, physiological and immunological reactions during the relocation process; 2) to identify biophysiological predictors of healthy adjustment to foreign work assignment and; 3) to increase knowledge...
Biosynthesis of leukotriene B4 in hematological malignancies
(2005-05-27)
Leukotrienes (LT) are biologically active metabolites of the fatty acid
arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA
2), this fatty acid can be converted to leukotrienes, lipoxins,
prostaglandins ...
Characterization of the BOLD signal in functional MRI
(2012-01-19)
parameters to the first echo, instead of conducting motion correction of the individual echoes independently. In study II, several aspects of brain mapping methods based on T2*-weighted imaging and T2* (R2*=1/T2*) mapping were quantitatively compared...
Structural enzymology of oxalate degradation in Oxalobacter formigenes
(2008-01-04)
Oxalic acid, as one of nature's most highly oxidised compounds, is toxic
to most organisms. It is introduced in the human body in the diet but
also as a waste product of cellular metabolism. Mammals do not posses ...
Factors affecting growth, differentiation and apoptosis of osteoblastic and osteosarcoma cells
(2008-10-17)
, inhibited adipocyte formation and enhanced osteoblast differentiation, while the inhibitor NAM had the opposite effect. In the second paper, osteoblastic cells from different origins, mouse, rat, and human, were treated with 1alpha,25(OH)2D3 and its analogue...
Studies of the synovial membrane in chronic rheumatic joint disease
(2006-04-26)
) is strongly expressed in RA lining cells, and also in sublining macrophages, synovial fibroblasts and endothelial cells. We also saw that mPGES-1 and COX-2 co-localised in cells from synovial fluid and tissue. Finally mPGES-1 and COX-2 were down...
Reproductive health in adolescent girls with special emphasis on menstrual disorders, bone health, sexuality and social factors
(2009-05-11)
Menstrual disturbances are common during adolescence, especially within the first 1-3 years after menarche, and are often explained by immaturity of the hypothalamic-pituitary-gonadal axis. However, little is known about ...
The neural control of rhythmic motor sequences
(2010-10-29)
Sequence learning is one of the most important functions of the motor system since almost every advanced motor skill consists of many component movements that need to be executed in sequential order. For successful performance ...
Effect of cycline-dependent kinase and matrix metalloproteinase inhibitors on hematopoietic and leukemic cells
(2008-10-24)
by roscovitine was consistent with apoptosis. Loss of mitochondrial membrane potential, release of cytochrome c, active fragment of caspase-3 and cleaved PARP were observed in all three cell lines, however, the pattern of activation of caspase-2 and -8 showed...
Regulatory networks of c-di-GMP signalling involved in biofilm formation, motility and host pathogen interactions in Salmonella typhimurium
(2013-08-09)
by binding the master regulator of flagella regulon FlhD4C2. Upon binding to FlhD4C2, STM1697 suppresses the functionality of FlhD4C2 to affect expression of downstream genes. Bioinformatic analysis revealed that the EAL domain proteins STM1344, STM1697...