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Violence towards health care personnel : prevalence, risk factors, prevention and relation to quality of care
(1998-11-18)
This thesis investigates the prevalence and nature of violence towards health care personnel and its implications for quality of care. The research presented here is based on a comprehensive perspective of violence as an ...
Single cell analysis of iPS derived neural stem cells and neurons
(2019-11-21)
In vitro derived neural stem cells can be used to model events of neurogenesis and neurodevelopmental dysfunction. Formation of stable neural stem cell environments relies on cellular components to stabilize cell-to-cell ...
Genetic studies in familial non-BRCA breast cancer
(2017-11-09)
Family history is an important risk factor for breast cancer, the presence of breast cancer in a first degree relative in general nearly doubles the risk and the risk increases with the number of affected relatives. ...
Modulation of hippocampal gamma oscillations by dopamine and serotonin receptor subtypes
(2014-05-23)
Normal brain function is dependent on the efficient and effective communication between the multitudes of microcircuits that it encompasses. The brain employs neuronal-network oscillations for large-scale communication in ...
Translational genomics of HIV-1 subtype C in India : molecular phylogeny and drug resistance
(2013-05-16)
This thesis describes the translational genomics of HIV-1subtype C in India from its origin to therapeutic response with the aim to improve our knowledge for better therapeutic and preventive strategies to combat HIV/AIDS. ...
Proteolysis of insulin-like growth factor-binding protein-1, -2 and -4 : function of fragments
(2011-12-21)
The insulin-like growth factors (IGF-I and IGF-II) stimulate cell growth, survival and differentiation, and have insulin-like activity. A family of six IGF-binding proteins (IGFBP-1 through -6) bind to IGFs with high ...
Association between diet and treatment results in patients with rheumatoid arthritis and systemic lupus erythematosus
(2016-11-07)
Rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are chronic autoimmune inflammatory diseases. The causes of these diseases are unknown and evidence indicates that a combination of both genetic and environmental ...
Osteoporosis in elderly women in primary health care
(2007-10-19)
Objective: All the studies are parts of the PRIMOS (Primary Health Care
and Osteoporosis) project. Study I investigates the relationship between
central Dual X-ray Absorptiometry (DXA) measurements of the hip and spine
and ...
The role of psychological stress in cervical and prostate carcinogenesis
(2017-05-23)
Psychological stress is common in everyday life, and has been well recognized as one of the major contributors to many mental and physical illnesses, such as mental disorders and cardiovascular diseases. The association ...
Hantaviruses, escapees from the death row : viral mechanisms towards apoptosis resistance
(2019-10-25)
Over the past decades, humanity has witnessed a constant stream of emerging pathogenic RNA viruses. The recurrent outbreaks of Ebola virus in Africa, the emergence of West Nile virus in North America and the sporadic but ...