Search
Now showing items 1-10 of 31
Mood disorders and consequences of pharmacological treatment
(2015-11-05)
Mental health issues are medical problems getting increased attention
throughout the world, and depression, only one among several types of
mental illnesses, are currently reported as the second leading cause of
disability ...
Respiratory activity in medulla oblongata and its modulation by adenosine and opioids
(1998-10-30)
From the moment of birth the complex neuronal networks generating breathing has to function continuously and adapt to the new postnatal environmental demands. This thesis aims at studying the perinatal development of ...
Periodontitis and invasive oral treatment in relation to myocardial infarction : epidemiological studies
(2019-11-25)
10 code I.21) within 4 weeks was investigated. Invasive dental treatment before a first myocardial infarction was not associated with an increased risk of a myocardial infarction (adjusted OR 0.98; 95% CI: 0.91−1.06). Conclusions: In nationwide...
Circulating immune complexes in atherosclerotic vascular disease
(2001-08-31)
We have investigated the association of the humoral immune factors
circulating immune complexes (CICs) and autoantibodies against
cardiolipin (aCL) and oxidatively modified LDL (oxLDL) to atherosclerotic
vascular diseases.
In ...
Epidemiology, risk and protective factors of self-immolation : a study from Iran
(2013-04-04)
Background: Suicide by self-burning (self-immolation) is one of the suicide methods that is far more common in low-middle income countries than in high-income ones. Iran is one of the countries that has a high rate of ...
Rheumatoid arthritis : pharmacological modulation of cytokines : aspects of clinical response and endocrine regulation
(2006-01-06)
Rheumatoid arthritis (RA) is a systemic inflammatory disease primarily affecting the joints. In the pathogenesis several cells of the immune systeme and messengers of the immune systeme, cytokines, are important. In this ...
Apoptosis and inflammation regulation after injury to the developing brain
(2015-09-25)
The brain shows greater plasticity in early life than in maturity, which paradoxically renders the organ more vulnerable to hypoxia-ischemia (HI)- and cranial irradiation (IR)- induced damage. Apoptosis after a HI insult ...
Epstein-Barr virus and genomic instability : a new look at the mechanisms of viral oncogenesis
(2010-12-20)
EBV is associated with a variety of lymphoid and epithelial malignancies but the mechanisms of oncogenesis are still not fully understood. The aim of the work described in this thesis was to assess whether induction of ...
A multi-omics approach to uncover estrogen receptor (ER) and activator protein 1 (AP-1) signaling networks in breast cancer
(2019-09-27)
breast cancer cell model with overexpression of ERβ in the absence of ERα. We used CRISPR/Cas9 system to knock out ERα in MCF7 breast cancer cells with stable Tet-Off-inducible ERβ expression. We found that only ERβ-expressing MCF7 cells displayed a...
Studies of the synovial membrane in chronic rheumatic joint disease
(2006-04-26)
Background: The synovial membrane (SM) outlines the inner cavity of synovial joints except for cartilage surfaces. The SM is the target organ of immune-mediated responses in chronic arthritis, including rheumatoid arthritis ...