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Rectal prolapse, internal rectal intussusception and the ripstein rectopexy : a clinical, physiological and radiological study
(1998-11-13)
faecal impaction and one ureteral stricture. Recurrencies and late complications were studied in 63 of the patients with rectal prolapse. Median length follow-up was 7.0 (range, 1.7-16.5) years. There was one recurrence. Forty-two of the patients...
When systemic lupus erythematosus (SLE) involves pain : occurrence and impact on daily life
(2018-11-19)
). At year 0, 84 patients with SLE and 91 age- and sexmatched controls from the general population completed self-assessment measures and questionnaires on pain using the Visual Analogue Scale (VAS) and the short-form McGill Pain Questionnaire (SF...
Mechanisms underlying mitochondrial function and biogenesis : implications for type 2 diabetes mellitus and obesity
(2012-12-21)
implicated as one possible cause of insulin resistance in several tissues; such as liver and skeletal muscle. The adipose-derived hormone leptin and the metabolic sensor 5’-AMP-activated protein kinase, are two key regulators that modulate intracellular fuel...
Biosynthesis of leukotriene B4 in hematological malignancies
(2005-05-27)
Leukotrienes (LT) are biologically active metabolites of the fatty acid
arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA
2), this fatty acid can be converted to leukotrienes, lipoxins,
prostaglandins ...
Single cell analysis of iPS derived neural stem cells and neurons
(2019-11-21)
In vitro derived neural stem cells can be used to model events of neurogenesis and neurodevelopmental dysfunction. Formation of stable neural stem cell environments relies on cellular components to stabilize cell-to-cell ...
Mechanisms controlling midbrain dopaminergic neuron development
(2016-11-25)
. This phenotype and the morphogenesis defect found in Wnt5a−/− mice were worsened in Wnt1−/−; Wnt5a−/− mice, indicating the existence of a previously unsuspected cooperation between Wnt1 and Wnt5a in mDA neuron development in vivo. Based on these results, we...
Prevention of growth failure caused by glucocorticoid treatment
(2023-03-10)
Children with chronic inflammation often suffer from growth failure and many of these children are treated with high doses of glucocorticoids (GCs). However, the underlying mechanisms of growth failure under conditions of ...
Immediate skin-to-skin contact for very preterm and low birth weight infants : from newborn physiology to mortality reduction
(2022-05-17)
infants, and from one register study. Studies I and II involved very preterm infants in Scandinavia, where study I (n=55) investigated the effect on infant temperature at one postnatal hour and study II (n=91) infant cardiorespiratory parameters during...
Bilateral cochlear implants in children : clinical and methodological studies
(2015-11-16)
A cochlear implant (CI) restores functional hearing in individuals with bilateral severe-
to-profound sensorineural hearing loss. Despite hearing loss in both ears, CIs
are usually provided unilaterally, excluding the ...
Robot-assisted laparoscopy and sentinel node biopsy in high risk endometrial cancer
(2018-11-15)
and 2016. Primary endpoint was paraaortic lymph node count. Patient-reported outcome (EORTC QLQ-C30 and the endometrial cancer module EN-24, EQ-5D for generic health status) was assessed before surgery and 12 months after surgery. Computed tomography (CT...