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Immunological characterisation of human anti-pig responses in vitro
(1998-04-03)
Xenotransplantation of organs or cells might solve the current problems of organ shortage. However, several problems need to be solved before xenotransplantation can become a successful clinical practice. Ethical, ...
Biosynthesis of leukotriene B4 in hematological malignancies
(2005-05-27)
Leukotrienes (LT) are biologically active metabolites of the fatty acid
arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA
2), this fatty acid can be converted to leukotrienes, lipoxins,
prostaglandins ...
Volume kinetic development and application
(2000-12-29)
Background: Fluid therapy is a cornerstone in shock resuscitation in a
such as treatment of anesthesia induce down regulation of the circulation
and also restores many different types of dehydrated states. Current
guidelines ...
Molecular studies of prognostic and etiological factors in childhood leukemia
(2015-04-29)
Acute lymphoblastic leukemia (ALL) is the most common cancer in childhood. It is caused
by the somatic acquisition of genetic abnormalities and malignant transformation of
immature lymphocytes in the bone marrow, most ...
Improving animal models to understand gene regulation in human diseases
(2021-10-29)
The role of animal models in understanding biological processes and their dysregulations in humans is imperative and established in the research community. While extensive resources and knowledge on the genetic information ...
Elevated fasting glucose levels in obese children and adolescents : prevalence and long-term consequences
(2016-01-29)
Background: Obesity in childhood and adolescents is a major concern in Sweden, as in many parts of the world. Already during the pediatric years is obesity associated with several metabolic complications, which often ...
Chemical genetics and immunomodulation in Salmonella enterica serovar typhimurium infection
(2015-04-08)
Salmonella sp. are versatile bacteria that survive and replicate in a plethora of environmental
niches and hosts, including humans. The illnesses caused by various serovars in humans
range from mild gastroenteritis to ...
Short-term exposure to ozone in relation to mortality and out-of-hospital cardiac arrest : exploring sensitive subgroups by previous hospitalizations
(2018-01-26)
Background: Several epidemiological studies have associated short-term ozone (O3) exposure with mortality, as well as with out-of-hospital cardiac arrest (OHCA) and other morbidity. Knowledge on which parts of the general ...
Pain relief following cesarean section : short and long term perspectives
(2015-04-17)
=130) or 40 ml saline solution (0.9%) (n=130), close to the fascia before closure of the wound. Morphine consumption, pain assessment by Numerical Rating Scale (NRS) and time to mobilization were recorded. Morphine requirements were significantly less...
Prognostic factors in breast cancer with a focus on the role of tumour proliferation
(2018-01-26)
Ki67 is the most commonly used marker of proliferation in breast cancer. The general aim of the thesis was to investigate the prognostic role of Ki67 and its interplay with other prognostic factors in breast cancer ...