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From a candidate region to gene characterization : analysis of three new genes with respect to meningioma tumorigenesis
(1998-05-27)
Meningioma is a common and usually benign tumor arising from the meninges covering the central nervous system (CNS). The yearly incidence of symptomatic meningiomas is 1.2 cases per 100 000 individuals but autopsy findings reveal an occurrence ten...
Recurrent abdominal pain in children : the concept, aetiology, diagnostics and prognosis
(2018-08-10)
study (III) revealed an increased risk of ap-FGID at five years in children growing up in families with a partly anthroposophic lifestyle, adjusted Odds Ratio 2.6 (95 % confidence interval: 1.1-5.9). No specific factor of the anthroposophic lifestyle...
Trajectory mapping of human embryonic stem cell cardiogenesis reveals lineage branch points and an ISL1 progenitor-derived cardiac fibroblast lineage
(2021-02-17)
A family of multipotent heart progenitors plays a central role in the generation of diverse myogenic and nonmyogenic lineages in the heart. Cardiac progenitors in particular play a significant role in lineages involved in ...
Regulation of mitosis : molecular analysis of the anaphase-promoting complex
(2000-11-10)
/G1 respectively. The Cdc20 is also known to interact with the spindle assembly checkpoint through a protein called Mad2. The mammalian APC/C consists of at least eleven subunits, for most of which the specific function is still unknown. Apc2 contains...
Intimate partner violence among women of reproductive age in Nigeria : magnitude, nature and consequences for reproductive health
(2011-01-05)
associated with the disclosure of IPV in the community sample (paper 2), the association between IPV and reproductive health outcomes in a nationally representative sample of Nigerian women (paper 3) and women and men’s attitudes towards IPV in a nationally...
To cut or not to cut? Episiotomy in vacuum extraction
(2022-04-05)
significantly higher rate of intrapartum cesarean section among women ≥40 years, both after spontaneous onset of labor (adjusted odds ratio (aOR) 3.07, 95%CI 2.81-3.35) and induction of labor (aOR 2.51, 95%CI 2.24-2.81). The risk of VE was also increased...
Small artery dysfunction : focus on preeclampsia and end-stage renal disease
(2012-04-18)
Background: End-stage renal disease (ESRD) and preeclampsia (PE) are associated with high risk of cardiovascular events and characterized by endothelial dysfunction. Resistance arteries are actively involved in the control ...
Detection and epidemiologic subtyping of Legionella pneumophilia using DNA-based molecular methods
(2003-11-14)
Legionella pneumophila causes 2 - 6 % of hospitalised pneumonia cases. Several community- and hospital-acquired outbreaks have been reported over the years. Legionnaires' disease (LD) or legionellosis is also a frequent cause of pneumonia amongst...
Integrated assessment of environmental and human health risks of antibiotic residues and resistance for environmental and health policy
(2021-04-27)
Background: Antibiotic resistance is a global health crisis and a serious threat to progress in achieving the Sustainable Development Goals. This requires a One Health response that recognises the link between human and ...
The role of SOXC transcription factors in B-cell development and lymphoid malignancies
(2017-09-15)
-off for SOX11-negative MCL and to investigate how quantitative expression related to positivity/negativity by IHC. A cut-off was defined, which resulted in misclassification of only 2/102 by qPCR and IHC. However, for the IHC SOX11+ cases, the qPCR analysis...