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Applications of microdialysis in studies of the adrenergic regulation of lipolysis in human skeletal muscle and adipose tissue
(1998-03-06)
skeletal muscle and adipose tissue.
The influence of blood flow on adipose tissue glycerol levels was investigated in human subcutaneous adipose tissue in situ (Paper 1). The microdialysis technique proved beneficial studying pharmacological interference...
Studies of the tumor-vasculature interface : role of TGF-beta 1-induced epithelial to mesenchymal transition
(2013-01-28)
roles of the coxsackie-and adenovirus receptor (CAR) for lymph vessel development, and the sphingosine-1-phosphate receptor (S1PR1) for blood vessel stabilization are presented. We expect the findings to have impact on our understanding of the interface...
Pituitary regulation of plasma lipoprotein metabolism and intestinal cholesterol absorption
(2005-11-18)
severely altered basal cholesterol metabolism (increased LDL-C, reduced HDL-C, suppressed LDLR and cholesterol 7alphahydroxylase, CYP7A1), concomitant with a striking loss of resistance to dietary cholesterol. Growth hormone (GH) substitution partly...
L-DOPA-induced signaling pathways and neuroepigenetic mechanisms in experimental parkinsonism and dyskinesia
(2014-11-07)
monophosphate (cAMP)/cAMP-dependent kinase (PKA)/ dopamine- and cAMP-regulated phosphoprotein of 32 kDA (DARPP-32) pathway. This exaggerated response results in excessive activation of the downstream extracellularregulated kinases 1 and 2 (ERK1/2) and mammalian...
Integrated assessment of environmental and human health risks of antibiotic residues and resistance for environmental and health policy
(2021-04-27)
Background: Antibiotic resistance is a global health crisis and a serious threat to progress in achieving the Sustainable Development Goals. This requires a One Health response that recognises the link between human and ...
Epidemiological studies on breast cancer risk factors and screening
(2023-09-27)
This thesis aims to enhance cancer prevention by investigating the factors and outcomes associated with false-positive (FP) mammography recalls, as well as understanding the association between breast cancer risk factors ...
To cut or not to cut? Episiotomy in vacuum extraction
(2022-04-05)
in women ≥40 years, both after spontaneous onset (aOR 1.71 95%CI 1.59-1.85), and induction of labor (aOR 1.45, 95%CI 1.28-1.65). We found no significant difference in rate of OASIS, episiotomy or low Apgar score. Overall, 79% of women ≥40 years had a...
Genotype-phenotype relations in SF3B1 mutated myelodysplastic syndromes with ring sideroblasts
(2016-10-28)
in the spliceosome gene SF3B1 are found in a majority of MDS-RS cases and are associated with the ring sideroblast phenotype and a favorable prognosis. MDS-RS is a usually slowly progressing disease of the elderly distinguished by an initial phase of erythroid...
Physiological status of bacteria used for environmental applications
(2006-12-22)
Several bacteria have properties of interest for biotechnological
applications, such as bioremediation of pollutants and biocontrol of
plant pathogens. In order to perform their intended tasks in the
environment the cells ...
The emergence and preservation of sick building syndrome : research challenges of a modern age disease
(1999-05-21)
Since the 1970ies, the sick building syndrome (SBS) has become a common health problem. It is usually defined as a state of ill health consisting of subjective symptoms from mucous membranes and skin, as well as of' general ...