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On the use of administrative databases in health care analyses
(1998-02-19)
The aim of this thesis is to demonstrate the potential of secondary administrative data sources in analyses of health care, its changes over time and its costs. The Swedish Cancer Registry the National Inpatient Registry ...
In vivo and in vitro studies of apolipoprotein CIII in diabetes
(2017-08-23)
Apolipoprotein CIII (apoCIII) is an important regulator of lipid metabolism and it is also known to have pro-inflammatory properties. From the point of view of diabetes it is interesting that both insulin deficiency and ...
Integrated assessment of environmental and human health risks of antibiotic residues and resistance for environmental and health policy
(2021-04-27)
Background: Antibiotic resistance is a global health crisis and a serious threat to progress in achieving the Sustainable Development Goals. This requires a One Health response that recognises the link between human and ...
Effects of combined oral contraceptives on hemostasis and biochemical risk indicators for venous thromboembolism and atherothrombosis
(2007-03-09)
Combined oral contraceptives (COCs) are one of the most common contraceptive methods in the world. Already a few years after their introduction, in the early 1960s, case reports were published showing associations between ...
Diabetes and puberty : studies on hormonal factors of importance to the blood glucose control
(2000-11-24)
It is well known that, in children with type 1 diabetes, metabolic control often deteriorates during puberty. Better understanding of the mechanisms that cause deterioration of blood glucose control can lead to improved ...
Cisplatin-induced tumor cell death signaling and potentiation by energy metabolism inhibitors
(2007-01-05)
Treatment of cancer is associated with challenges including the tumor development of resistance. By elucidating intracellular signal transduction pathways elicited by therapy it is possible to identify structures and ...
The effect of alpha-HGA on HIV-1 replication
(2009-03-13)
Different classes of anti HIV-1 drugs are now available for treatment of HIV-1 infection. Although improved, these drugs show adverse effects and their long-term efficiency is severely hampered by the emergence of resistant ...
Studies on HIV-1 core assembly
(2007-11-02)
The main objective of this thesis was to define the roles of Gag (p55), in particular, the capsid (CA, p24) protein in human immunodeficiency virus type 1 (HIV-1) particle assembly. More specifically, i) to determine the ...
Self-reported fecal incontinence and quality of life among gynecological cancer survivors
(2010-05-07)
Gastrointestinal symptoms following pelvic radiotherapy are common;
however, selfreported descriptions of gastrointestinal symptoms and their
impact on daily life among gynecological cancer survivors are rare in ...
Developmental origins of polycystic ovary syndrome : role of early adverse life events on adult health
(2020-03-17)
The research focus of this thesis is polycystic ovary syndrome (PCOS), the most common endocrine disorder among women of reproductive age, associated with reproductive, cardio-metabolic, and mental health complications. ...