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Processing of live and heat inactivated Sendai virus for presentation on MHC class I molecules
(1997-11-07)
The present thesis deals with processing of antigens from live and heat inactivated Sendai virus and their loading on MHC class I molecules for presentation to CTL. In paper I it was observed surprisingly that T2 cells (T2 ...
Economic aspects of chronic diseases : multiple sclerosis and diabetes mellitus
(2001-11-02)
to a total cost of
4.9 billion SEK calculated in 1998 using a bottom-up method. How costs
are defined and calculated will also affect the results. The top-down
study on diabetes showed the direct costs to be 1.6 billion SEK. However,
this study only...
Immune modulation in chronic HBV and HCV infection
(2000-05-26)
Chronic viral hepatitis is a major health problem worldwide. The two major viral causes for chronic hepatitis are the hepatitis B (HBV) and C viruses (HCV). HBV is a DNA virus with a rather limited genetic variability ...
Screening for atrial fibrillation in high-risk individuals : a stroke preventive effort
(2016-10-31)
control group or to attend a screening study. Of the 13,331 individuals who were invited, 7,173 (54%) participated. New AF was detected in 218 participants (3.0 %, 95% confidence interval (CI) 2.7-3.5) using twice daily intermittent ECG recordings for 14...
An epidemiological study on nasopharyngeal carcinoma
(2021-10-25)
Nasopharyngeal carcinoma (NPC) is a malignancy known for its unique geographic and ethnic distribution characterized by particularly high incidence in southern China, Southeast Asia, and North and East Africa, but being ...
Determination of transcription factor binding specificities
(2015-11-19)
The term "genetic code" refers to the way in which the information encoded in nucleic acids
is converted into the amino-acid sequence of proteins. There is however also a second genetic
code, one that is used by the cells ...
Chromosome aberrations and environmental exposures in acute leukemia
(2009-08-19)
distribution): 2-554, (P=0.002), in all different professions exposed to organic solvents: OR: 4.9; 95%CI: 2.2-12.1, (P<0.001) and in drivers: OR: 3.0, 95%CI: 1.1-9.2 (P=0.02). Multivariate analysis showed that the significances remained, after consideration...
Cardiac remodeling in aortic and mitral valve disease : a simulation study with clinical validation
(American Psychological Association, 2019-09-03)
Background: Remodeling is an important long-term determinant of cardiac function throughout the progression of heart disease. Numerous biomolecular pathways for mechanosensing and transduction are involved. However, we ...
Inflammatory response in periodontal tissue in children with Down syndrome
(2013-05-15)
as percentage of bleeding on probing (BOP%). In all subjects, gingival crevicular fluid (GCF) was collected from six sites with paper strips, and levels of prostaglandin E2 (PGE2), leukotriene B4 (LTB4), and MMP-9 were analysed using RIA and ELISA kits. BOP...
Methods in pharmacoepidemiology : four studies, four settings
(2010-04-30)
In the present thesis, four studies using four different settings and
designs are presented in which associations between pharmacological
treatments and possible adverse drug reactions are investigated; some
methodological ...