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Multiple endocrine neoplasia type 1 : clinical and molecular characterization
(1997-10-17)
This thesis is based on clinicopathologic and genetic studies of MEN1 and MEN1-like syndromes. Linkage to the MENl locus in chromosome 11q13 was confirmed in the largest known MEN1 family and 5 Swedish MEN1 families. An ...
Elevated fasting glucose levels in obese children and adolescents : prevalence and long-term consequences
(2016-01-29)
Background: Obesity in childhood and adolescents is a major concern in Sweden, as in many parts of the world. Already during the pediatric years is obesity associated with several metabolic complications, which often ...
Interventions during pregnancy and labor and obstetric outcome
(2011-09-16)
Objectives: The overall objective with the present thesis was to assess pregnancy and delivery associated risk factors for adverse pregnancy outcomes. Specific aims were : 1) to analyze the association between fetal size ...
Responsive nanostructured materials for bioanalyte detection and triggered antimicrobial therapy
(2022-04-29)
Inorganic nanomaterials are attractive candidates for biomedicine as they can offer increased stability including light, temperature and chemical stability while also offering the benefits of high-throughput synthetic ...
Morbidity and childbirth in myeloproliferative neoplasms
(2023-03-31)
Myeloproliferative neoplasms (MPN) are a family of chronic hematologic cancers, characterized by excess proliferation of myeloid cell lineages, or fibrosis of the bone marrow. Patients with MPN generally have a long expected ...
Cisplatin-induced tumor cell death signaling and potentiation by energy metabolism inhibitors
(2007-01-05)
Treatment of cancer is associated with challenges including the tumor development of resistance. By elucidating intracellular signal transduction pathways elicited by therapy it is possible to identify structures and ...
Cell lineage analysis in humans
(2021-07-29)
Delineating a cell’s history, where it came from and what has happened to it, can provide clues as to how tissues and organs are formed and function in the healthy state and in disease. The gold standard for tracing the ...
Body size and physical activity : epidemiological studies on children and young adults
(2007-05-25)
The overall aim of this thesis was to increase the knowledge about
different aspects of body size and physical activity among Swedish
children and young adults. Specific aims were: (i) to investigate how
BMI-distributions ...
Long-term exposure to air pollution from road traffic and development of airway and allergic diseases in children
(2012-11-22)
Allergic diseases are of great public health concern and constitute one of the most prevalent childhood illnesses. Air pollution exposure is related to several types of adverse health effects. There are, however, limited ...
Is it all about the money? The effects of low and high cost simulator training scenarios in surgical training
(2020-05-12)
Background: The learning process is complex and dependent on several factors such as for instance, the environment to learn, prior knowledge and distinct abilities, motivation, goal-orientation as well as the effects of ...