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The effect of galanin message-associated peptide in spinal sensory processing
(1997-11-07)
Galanin message associated peptide (GMAP), the C-terminal flanking peptide in the precursor protein of galanin, has been studied to established whether this peptide has its own biological action. With some exceptions, GMAP ...
Toxicological aspects of bile acids and human fecal water on cultured human colon carcinoma cells
(2001-05-11)
Colorectal tumorigenesis involves activation of mutations in
proto-oncogenes, such as ras and c-myc, as well as mutations that
inactivate tumor suppressor genes including the APC and the p53 gene.
These genetic events, ...
Novel in vitro methods aiming at improving fertility preservation
(2021-11-11)
The well-established fertility preservative methods for female cancer patients include the cryopreservation of embryos, mature oocytes and ovarian tissue before the initiation of gonadotoxic cancer treatment. Due to a ...
Generation and investigation of neural microenvironment in health and disease
(2019-10-09)
Cells in our body are under the constant influence of intrinsic and extrinsic factors that modulate their behavior. Early on, starting during the development of the organism, growth factors, nutrients, oxygen, the extracellular ...
Getting in and out of shape : relevance for organ formation and cancer
(2014-09-11)
A central question during development is how single cells form functional multi-cellular organ structures. The high reproducibility indicates intricate synchronization of cellular behaviors such as migration, proliferation ...
Cost analysis and policy implications in psychiatric care
(2009-04-01)
in Sweden in 2001 (Study I) was estimated at MSEK 85 774 (M€ 9 426, €1= SEK9.1). Indirect costs were totally predominant and constituted about 80% of the total cost, i.e. production losses due to early retirement, sickness absence and premature death...
Structural studies of lumazine synthases : thermostability, catalytic mechanism and molecular assembly
(2005-12-27)
Riboflavin, also known as vitamin B2, is biosynthesized in plants, bacteria, archaea and fungi. The primary biological function of riboflavin is related to its existence as a component of the two coenzymes, flavin ...
Type 1 diabetes in pregnancy : perinatal outcome with special reference to fetal macrosomia
(2012-04-16)
.2 million controls we found significantly increased risks of all adverse outcomes in women with T1DM: adjusted odds ratios: severe preeclampsia: 4.47 (3.77-5.31), Caesarean delivery: 5.31 (4.97-5.69), stillbirth: 3.34 (2.46- 4.55), perinatal mortality: 3...
Stress reactivity, cognitive functioning and hippocampal morphology in exhaustion disorder, and development of a self rating scale for exhaustion disorder, KEDS
(2011-12-27)
Stress is considered a major health problem in modern society and a prominent reason behind the long term sick leave (LTSL). Chronic stress may give rise to feelings of irritation and fatigue or exhaustion and may precipitate ...
Single-cell RNA sequencing for subtype discovery in Plasmodium falciparum and mammalian cells
(2019-04-25)
Since the dawn of massively parallel sequencing technologies in mid-2000s their utility in profiling the expression of genes in a genome-wide fashion has matured and progressed from cell populations to individual cells. ...