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Root surface conditioning in periodontal treatment
(1997-09-05)
Marginal periodontal healing following both invasive and non-invasive therapies is influenced by a large number of systemic and local factors. In order to optimize healing, a lot of effort is put into minimizing possible ...
Topoisomerase II and drug resistance in leukemic cells
(2001-05-21)
than the pop negative cells (p=0.01). About 26% (12/46) of all samples had detectable topo IIalpha mRNA expression and 56% (26/46) had detectable topo IIbeta mRNA. Experimental results were compared with treatment response in patients with AML. We found...
Health economic epidemiology of obstructive airway diseases
(2006-05-18)
were estimated at about SEK 9.1 billion (95% Cl 6.1-12.8). As COPD to a great extent is an underdiagnosed disease, the total costs were divided into subjects with and without a physician diagnosis of COPD. The costs for undiagnosed subjects accounted...
Diabetes and puberty : studies on hormonal factors of importance to the blood glucose control
(2000-11-24)
It is well known that, in children with type 1 diabetes, metabolic control often deteriorates during puberty. Better understanding of the mechanisms that cause deterioration of blood glucose control can lead to improved ...
Improving animal models to understand gene regulation in human diseases
(2021-10-29)
The role of animal models in understanding biological processes and their dysregulations in humans is imperative and established in the research community. While extensive resources and knowledge on the genetic information ...
Endothelial dysfunction in atherosclerosis and type 2 diabetes : clinical and molecular studies of the role of endothelin and arginase
(2018-05-08)
Background: Atherosclerosis is a modern world scourge and the number of people worldwide diagnosed with type 2 diabetes (T2D) is on the rise, causing much morbidity and mortality. Endothelial dysfunction (ED) is an early ...
Leukotriene A4 hydrolase : identification of amino acid residues involved in catalyses and substrate-mediated inactivation
(2001-09-14)
Leukotriene (LT) A4 hydrolase catalyzes the committed step in the
biosynthesis of LTB4, a classical chemoattractant and immuine-modulating
lipid mediator involved in inflammation, host-defense against infections,
and ...
Moderately preterm infants : studies on length of hospital stay and neonatal outcome
(2011-05-03)
Objective: Moderately preterm infants account for a large proportion of admissions and bed-days in neonatal units. Determinants of length of hospital stay, contemporary measures of morbidity by gestational week and risk ...
Feeding the very low birth weight infant : short and long term effects of tube feeding methods in early postnatal life
(2012-05-25)
infants showed a significantly higher risk of a behavioural stress response to feeding compared with continuous-fed infants at 15 days of age, adjusted odds ratio 4.1 (95% CI: 1.1 - 15.4) with a similar result at 32 weeks, adjusted OR 4.2 (95% CI: 1.0 - 17.8...
Regulatory function of homeobox genes in the development of C. elegans
(2010-09-10)
The nematode worm Caenorhabditis elegans has been widely used as a genetic model for over 40 years to investigate developmental control genes. In this thesis, I studied the roles of several homeobox genes and a novel RNA ...