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The in vivo metabolism of Benzo(a)pyrene studied by chromatography in combination with mass spectrometry
(1997-09-08)
metabolite of BP in this fraction. Trace levels of metabolites probably related to the well-known activation pathway leading to BP-7,8-dihydrodiol-9,10-epoxide (BPDE) were detected, e.g. the trans-7,8-diol and tetrols. The presence of a high abundance...
Identification of novel pathways of regulation of AHR and HIF-1 function
(2018-09-14)
mechanism behind the results presented in paper II. Muscle cells show the highest FIH levels on tissue level and we observed elevated histone 3 lysine 9 dimethyl (H3K9me2) levels in FIH null mice. Further work showed significantly increased methylation...
Determinants of hearing impairment in Swedish hunters : an e-epidemiological approach
(2016-04-08)
Background: 290 236 persons bought a hunting license in Sweden 2014/15. Hunters are
spread all over the country and come from all socioeconomic groups. Recreational fiearms
can produce peak noise levels between 156-164 ...
Reproductive health in adolescent girls with special emphasis on menstrual disorders, bone health, sexuality and social factors
(2009-05-11)
Menstrual disturbances are common during adolescence, especially within the first 1-3 years after menarche, and are often explained by immaturity of the hypothalamic-pituitary-gonadal axis. However, little is known about ...
Cost analysis and policy implications in psychiatric care
(2009-04-01)
in Sweden in 2001 (Study I) was estimated at MSEK 85 774 (M€ 9 426, €1= SEK9.1). Indirect costs were totally predominant and constituted about 80% of the total cost, i.e. production losses due to early retirement, sickness absence and premature death...
Studies of the synovial membrane in chronic rheumatic joint disease
(2006-04-26)
Background: The synovial membrane (SM) outlines the inner cavity of synovial joints except for cartilage surfaces. The SM is the target organ of immune-mediated responses in chronic arthritis, including rheumatoid arthritis ...
Healthcare financing challenges and opportunities to achieving universal health coverage in the low- and middle-income country context
(2020-02-05)
and the richest households, respectively. The poverty rate rose by 5.5% (9.0 million individuals) due to OOP payments. In study II, we observed that approximately 87% of the informal workers were willing to pay for the CBHI. The average weekly WTP was 22.8 BDT [95...
Traumatic patellar dislocation in childhood : late effects on knee function and cartilage quality
(2016-02-24)
Background and aim: Acute patellar dislocation affects approximately 1:1000 healthy children 9-
15 years of age, and up to 50% are at risk for recurrent dislocations. In adults the condition is
associated with long-term ...
E-epidemiology : adapting epidemiological methods for the 21st century
(2009-08-28)
The traditional methods in epidemiological data collection are both costly and time consuming and less convenient for longitudinal large-scale studies. During the last decades, epidemiological studies suffer from low ...
Ultrasound assessment and risk prediction in women with endometrial cancer
(2020-01-09)
Background: Endometrial cancer is the most common gynecological cancer in the industrialized world, constituting 4.5% of all cancer in Swedish women. Standard surgery is hysterectomy and bilateral salpingo-oophorectomy, ...